A client has been diagnosed with gouty arthritis and has begun taking allopurinol (Zyloprim). What is important for the nurse to discuss with the client regarding this medication?
1. The medication should be taken with food, and intake of liquids should be increased throughout the day.
2. Diarrhea and nausea may occur soon after therapy begins and will subside with no treatment.
3. The client should call the doctor if severe headaches occur after taking the medication.
4. The client should start to feel some pain relief within the first 24 hours after taking the medication.
Answer: 1
The client must take the medication with food to avoid gastrointestinal upset. The medication is being given because of the hyperuricemia; therefore the client needs to increase fluids to flush out the excess uric acid. It will take the medication several days to achieve maximum effectiveness; pain relief will not be immediate. Diarrhea, nausea, and headache are not common side effects.