A client is taking allopurinol (Zyloprim) 200 mg by mouth every day. Which statement by the client indicates an understanding of the nurse's instruction?
1. "My diet will consist of more meat and fewer sugars."
2. "I need to drink at least ten 8-ounce glasses of water a day."
3. "I should increase my intake of dairy products."
4. "This medication should be taken on an empty stomach."
Answer: 2
Allopurinol (Zyloprim) reduces uric acid concentration in the serum and in the urine. It must be taken with at least 8 or more glasses of water to increase urine flow to reduce the risk of renal calculi formation. Increasing protein, limiting sugar, and increasing dairy products do not affect the action of Zyloprim. The medication may cause gastric irritation, and it may be taken with food to decrease incidence of gastric irritation.